Taylor Potts threw for 388 yards and two touchdowns as Texas Tech beat Oklahoma 41-13 on Saturday for its most lopsided win ever over the Sooners.
Baron Batch ran for 136 yards and two scores for the Red Raiders (7-4, 4-3 Big 12), who became bowl eligible for the 16th straight season.
Oklahoma (6-5, 4-3) has its most losses since going 7-5 in 1999. It was just the fifth win in 17 meetings for Texas Tech against the Sooners, and the Red Raiders had never won by more than 10 points in the series.
The margin was a stunning reversal from last season, when the Sooners crushed Texas Tech 65-21 to end the Red Raiders' national championship hopes. Oklahoma hadn't lost this badly since falling to Texas 45-12 in 2005.
Alex Torres had his best game of the season with 11 catches for 163 yards.