The safety of popular bone drugs like Fosamax and Boniva is the focus of an FDA advisory panel today. Bisphosphonates help reduce hip and spine fractures, but experts are concerned about possible side effects -- like bone brittleness -- that may occur with long term use. The panel is considering whether to recommend requiring women to take a 'drug holiday' to allow their body to take a break from the drugs. The FDA will also conduct a review of medical evidence to determine if bisphosphonates are safe and effective when used longer than three to five years. An estimated four million women in the United States take bisphonsphonates.
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