Cholesterol Lowering Drugs Tested on Children - KCBD NewsChannel 11 Lubbock

7/20/04

Cholesterol Lowering Drugs Tested on Children

Lots of times we hear "don't try this on kids" because it hasn't been tested yet in kids. Well, cholesterol lowering drugs have now been tested on more than 200 children with high cholesterol, and the news is good.

The two year study shows, that just like adults who use Statins, the kids taking cholesterol lowering drugs ended up with much lower levels than the kids taking a sugar pill. Likewise, the medicine also helped reduce plaque build-up in the heart arteries of children with no side effects of organ damage. You can read more in the Journal of the American Medical Association.

The study tested the drug Pravastatin which belongs to the class of drugs known as Statins. It lowers cholesterol by blocking the enzyme in the liver that is responsible for making cholesterol.

The study included 214 children ages 8 to 18 who were recruited between December 1997 and October 1999 and followed up to two years. After the initiation of a fat-restricted diet and encouragement of regular physical activity, 106 children were randomly assigned to receive treatment with 20 to 40 milligrams per day of Pravastatin, and 108 were assigned to receive a placebo tablet.

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