The second U.S. case of Mad Cow disease was in an animal from Texas that was killed last November.
The Associated Press quotes two government officials, who spoke on condition of anonymity. The U.S. Department of Agriculture planned an announcement later. The AP reports USDA officials traced the infected cow to a rendering plant for animals unfit for human consumption.
Ag authorities have said the cow was a so-called "downer" that couldn't walk. The animal was more than 8-years-old when it arrived at the plant.
Governor Rick Perry's late Wednesday issued a statement urging the public to be calm. Perry says people can have the highest confidence in the beef supply, and that he'll continue to eat red meat.
The U.S. banned using cattle parts in such feed since 1997 following an outbreak of mad cow disease in Britain.
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Gov. Perry Responds to Mad Cow Confirmation