Researchers at Duke University Medical Center have identified the first gene believed to be related to Testicular Cancer in men. They are calling the gene Hiwi, and they say that 63% of men who inherit an overactive form of this gene are more prone to develop a type of Testicular Cancer called Seminoma. According to the National Cancer Institute, Testicular Cancer is the most common form of cancer in Caucasian men between the ages of 15 and 45. So they are hopeful this research could lead to genetic testing to predict a man's potential for developing Testicular Cancer.
Lead researcher: Haifan Lin, Ph.D., Associate Professor of Cell Biology, Duke. Dr. Lin's research was funded by the National Institutes of Health. Research based on samples from 35 patients in which 63% expressed the Hiwi gene in abnormally high levels. The Hiwi gene was mapped to a region on the long arm of chromosome 12.
This study is published in the Thursday, June 6th issue of Oncogene.